Cardiovascular disease accounts for 30% of mortality in the UK and the developed world, and is the fastest increasing disease in the developing world lifestyle increasingly conforms to that found in Western countries. There exist a multiplicity of therapies for cardiovascular disease and its antecedent risk factors. Cardiovascular disease is preventable. Many countries have started to prevent cardiometabolic disease through interventions to reduce smoking, improve diets, persuade people to reduce their weight and take more exercise; these are slowly bearing fruit yet there remain those in whom cardiometabolic disease has already become established. These patients now occupy the services of a multiplicity of medical specialties and professionals allied to medicine. This handbook is intended for those with an interest in hyperlipidaemia and cardiovascular risk working either in primary or secondary care. It reflects the experiences of difficult cases that the authors have seen in the lipid and prevention clinics of specialist primary and secondary care over the last 2 decades. It will provide some answers to those seeking strategies to manage more complex cases. 1. Concise reading of 56 specific patient problems with cardiovascular risk 2. Comprehensive coverage of primary and secondary prevention, hyperlipidaemias and hypertension 3. Highly qualified and experienced doctors have co-authored this book.

Table of Contents:
Section 1 Primary Prevention 1. Assessment of cardiovascular risk 2. Morbid obesity 3. Metabolic syndrome 4. Vegetarian 5. Indian Asian 6. African 7. Polygenic hypercholesterolaemia 8. Extremely elderly 9. Women 10. Screening for hyperlipidaemias and cardiovascular risk 11. Impaired glucose tolerance 12. Low high-density lipoprotein cholesterol 13. Combination fibrate-statin therapy 14. Low high-density lipoprotein cholesterol in secondary prevention Section 2 Secondary Prevention 15. Coronary heart disease 16. Unstable angina 17. Stroke 18. Peripheral vascular disease 19. Aortic stenosis 20. Erectile dysfunction 21. Atrial fibrillation 22. Renal artery stenosis 23. Homocysteine and cardiovascular disease 24. Type 1 diabetes mellitus 25. Type 2 diabetes mellitus 26. Type 2 diabetes mellitus and microalbuminuria 27. Lipoprotein(a) and cardiovascular risk 28. Chronic cardiac failure Section 3 Secondary Hyperlipidaemias and Side-effects 29. Hypothyroidism 30. Alcohol-associated hyperlipidaemia 31. Non-alcoholic fatty liver disease 32. Lipid-lowering drugs and rhabdomyolysis 33. Primary biliary cirrhosis 34. Multiple drug intolerances 35. Gastrointestinal side-effects of lipid-lowering drugs 36. Neuropathy and statins Section 4 Genetic Hyperlipidaemias 37. Familial hypercholesterolaemia 38. Paediatric familial hypercholesterolaemia 39. Homozygous familial hypercholesterolaemia 40. Familial combined hyperlipidaemia 41. Remnant hyperlipidaemia 42. Chylomicronaemia 43. Glycogen storage disease and dyslipidaemia 44. Fabry disease Section 5 General Medicine and Hyperlipidaemia 45. Pregnancy and hyperlipidaemia 46. HIV dyslipidaemia 47. Autoimmune disease and atherosclerosis 48. Nephrotic syndrome 49. Chronic renal failure 50. Renal transplant 51. Hypopituitarism Section 6 Hypertension 52. Hypertension 53. Resistant hypertension 54. Phaeochromocytoma 55. Hyperaldosteronism Section 7 Dermatological Dyslipidaemia 56. Retinoid-induced dyslipidaemia 57. Mycosis fungoides, bexarotene and T-cell lymphoma General index