This book constitutes the proceedings of the Second International Conference on Optimization, Learning Algorithms and Applications, OL2A 2022, held in Bragança, Portugal, in October 2022. The 53 full papers and 3 short papers were thoroughly reviewed and selected from 145 submissions. They are organized in the topical sections on Machine and Deep Learning; Optimization; Artificial Intelligence; Optimization in Control Systems Design; Measurements with the Internet of Things; Trends in Engineering Education; Advances and Optimization in Cyber-Physical Systems; and Computer vision based on learning algorithms.

Table of Contents:
Machine and Deep Learning.- Techniques to Reject Atypical Patterns.- Development of an Analog Acquisition and Conditioning Circuit of Surface Electromyogram and Electrocardiogram Signals.- Methodology Applied to the Development of Sensor Architectures Dedicated to Unmanned Aerial Vehicles.- Is Diabetic Retinopathy Grading Biased by Imbalanced Datasets?.- Attention Mechanism for Classification of Melanomas.- Volume Estimation of an Indoor Space with LiDAR Scanner.- Good Practices in the Management of Virtual Environments with Emphasis on Security.- A Rule Based Procedural Content Generation System.- A Hybrid Approach to Operational Planning in Home Health Care.- Multi VLAN Visualization in Network Management.- A Review of Dynamic Difficulty Adjustment Methods for Serious Games.- Anxiety Monitoring System: A Preliminary Approach.- Optimization.- Statistical Analysis of Voice Parameters in Healthy Sub-jects and with Vocal Pathologies - HNR.- Integrated Feature Selection andClassification Algorithm in the Prediction of Work-Related Accidents in the Retail Sector: A Comparative Study.- Traffic Light Optimization of an Intersection: a Portuguese Case Study.- Combined Optimization and Regression Machine Learning for Solar Irradiation and Wind Speed Forecasting.- An Improved Multi-Threaded Implementation of the MCSFilter Optimization Algorithm.- Integer Programming Applied to Wireless Sensor Networks Topology Optimization.- Two Clustering Methods for Measuring Plantar Temperature Changes in Thermal Images.- A Multi-objective Approach for the Menu Planning Problem: a Brazilian Case Study.- Artificial Intelligence.- Stock-Pred: The LSTM Prophet of the Stock Market.- Confidence-Based Algorithm Parameter Tuning with Dynamic Resampling.- Classification of Leftovers from the Stock Cutting Process.- Active GA Accelerated by Simulated Annealing to Solve SPP in Packet Networks.- Long-Term Person Reidentification: Challenges and Outlook.- Sentiment Analysis applied to IBOVESPA Prediction.- F0, LPC, and MFCC Analysis for Emotion Recognition Based on Speech.- Solanum lycopersicum - Fusarium oxysporum Fo47 Interaction Study using ML Classifiers in Transcriptomic Data.- Smart Data Driven System for Pathological Voices Classification.- Gene Expression Analysis of Solanum lycopersicum - Bacillus megaterium Interaction to Identify Informative Genes using Machine Learning Classifiers.- A Kernel Clustering Algorithm Based on Diameters.- Forecasting Omicron Variant of Covid-19 with ANN Model in European Countries – Number of Cases, Deaths, and ICU patients.- Anomaly Detection using Smart Shirt and Machine Learning: A Systematic Review.- Decision Making System to Support the Cost of Ordered Products.- Optimization in Control Systems Design.- Analysis of Topological Characteristics Impacting the Allocation of Controllers in a SD-WAN Network: RNP Case.- A Hybrid Approach GABC-LS to Solve mTSP.- On the Complexity of a Linear Programming Predictor-Corrector Algorithm using the Two Norm Neighborhood.- Modelling and Control of a Retrofitted Oven for SMD Reflow.- Measurements with the Internet of Things.- Investigation of the Partial Discharges in the High Voltage Measurement Transformers.- Smart Systems for Monitoring Buildings - An IoT Application.- Map Coverage of LoRaWAN signal's Employing GPS from Mobile Devices.- Node Assembly for Waste Levels Measurement: Embrace the Smart City.- Trends in Engineering Education.- Data Analysis Techniques Applied to the MathE Database.- Evolution of Soft Skills for Engineering Education in the Digital Era.- Communication in Educational Robots: From Coordination to IoT Systems.- Educational Testbed in the context of Industry 4.0 and 5.0: Literature Review.- Advances and Optimization in Cyber-Physical Systems.- Adaptive Environment System to Manage Comfort Preferences and Conflicts.- Asynchronous and Distributed Multi-agent Systems: an Approach through Actor Model.- Stock Management Improvement in a Nursing Ward using Lean Approach and Mathematical Modelling.- Monitoring Electrical and Operational Parameters of a Stamping Machine for Failure Prediction.- Computer vision based on learning algorithms.- Super-Resolution Face Recognition: an Approach Using Generative Adversarial Networks and Joint-Learn.- Image Processing of Petri Dishes for Counting Microorganisms.- Caenorhabditis Elegans Detection using YOLOv5 and Faster R-CNN Networks.- Object Detection for Indoor Localization System.- Classification of Facial Expressions under Partial Occlusion for VR Games.- Machine Learning to Identify Olive-tree Cultivars.